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The CNS contains the brain and spinal cord. White matter includes all of the nerves, and much of the interior of the brain and spinal cord.
Nerves that exit from the cranium are called cranial nerves while those exiting from the spinal cord are called spinal nerves. The vertebrate nervous system can also be divided into areas called grey matter "gray matter" in American spelling and white matter. The next major development in neuroanatomy came from the Greek Alcmaeon, who determined that the brain and not the heart ruled the body and that the senses were dependent on the brain.